Orgo-Seq – integration of single-cell and bulk transcriptomic data to identify cell type specific-driver genes
Cerebral organoids can be used to gain insights into cell type specific processes perturbed by…
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CLIPreg – Constructing translational regulatory networks from CLIP-, Ribo- and RNA-seq
The creation and analysis of gene regulatory networks have been the focus of bioinformatics research…
Microarray-based synthesis of large oligonucleotide pools as a source for distinct, non- random NGS barcodes
Researchers have demonstrated that, despite the intrinsically low raw accuracy of long-read sequencing technologies, multiplex…
Nuclear oligo hashing improves differential analysis of single-cell RNA-seq
Single-cell RNA sequencing (scRNA-seq) offers a high-resolution molecular view into complex tissues, but suffers from…
New single-cell RNA-sequencing method developed at IOB has potential to become universal tool of choice
A new single-cell RNA-sequencing protocol developed at IOB enables the detection of a significantly higher number of…
Characterization and sequence mapping of large RNA and mRNA therapeutics using mass spectrometry
Large RNA including mRNA (mRNA) has emerged as an important new class of therapeutics. Recently,…
A LAMP sequencing approach for high-throughput co-detection of SARS-CoV-2 and influenza virus in human saliva
The COVID-19 pandemic has created an urgent need for rapid, effective, and low-cost SARS-CoV-2 diagnostic…
IMGG – integrating multiple single-cell datasets through connected graphs and generative adversarial networks
There is a strong need to eliminate batch-specific differences when integrating single-cell RNA-sequencing (scRNA-seq) datasets…
Halo-seq – An RNA proximity labeling method for the isolation and analysis of subcellular RNA populations
The subcellular localization of specific RNA molecules promotes localized cellular activity across a variety of…