LORAX-seq – pioneering technique reveals new layer of human gene regulation
A technique can determine for the first time how frequently, and exactly where, a molecular…
Browsing: Publications
A novel technique for advanced data processing and analysis
Statisticians at the National University of Singapore (NUS) have introduced a new technique that marks…
Variation in mRNA expression pathways associated with worse ICH outcomes
Intracerebral hemorrhages (ICH), one of the most severe types of stroke, are caused when a…
Cell-type deconvolution of bulk-blood RNA-seq reveals biological insights into neuropsychiatric disorders
Genome-wide association studies (GWASs) have uncovered susceptibility loci associated with psychiatric disorders such as bipolar…
RNA splicing regulation discovery provides insight into bone diseases
In today’s aging societies, diseases affecting the bones and joints are becoming increasingly common. For…
Researchers use nanopore direct RNA sequencing to analyze viral RNA modifications
Modifications on viral RNAs (vRNAs), either genomic RNAs or RNA transcripts, have complex effects on…
A single cell RNAseq benchmark experiment embedding “controlled” cancer heterogeneity
Single-cell RNA sequencing (scRNA-seq) has emerged as a vital tool in tumour research, enabling the…
New research improves accuracy of molecular quantification in high throughput RNA sequencing
A team at NDORMS has developed a new approach to significantly improve the accuracy of…
Robust detection of clinically relevant features in single-cell RNA profiles of patient-matched fresh and FFPE lung cancer tissue
Single-cell transcriptional profiling reveals cell heterogeneity and clinically relevant traits in intra-operatively collected patient-derived tissue.…
A reliable transcriptomic risk-score applicable to FFPE biopsies improves outcome prediction in localized prostate cancer
Clinical manifestation of prostate cancer (PCa) is highly variable. Aggressive tumors require radical treatment while…