Single-cell spatial analysis identifies regulators of brain tumor–initiating cells
Glioblastomas (GBM) are aggressive brain tumors with extensive intratumoral heterogeneity that contributes to treatment resistance.…
Glioblastomas (GBM) are aggressive brain tumors with extensive intratumoral heterogeneity that contributes to treatment resistance.…
Researchers at Colorado State University have developed tiny-count, a highly flexible counting tool that allows for…
The count table, a numeric matrix of genes × cells, is the basic input data…
Researchers at Children’s Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA)…
Undoubtedly, single-cell RNA sequencing (scRNA-seq) has changed the research landscape by providing insights into heterogeneous,…
The main critical step in single-cell transcriptomics is sample preparation. Several methods have been developed…
Formalin-fixed paraffin-embedded (FFPE) tissues constitute a vast and valuable patient material bank for clinical history…
Each gene in our DNA has a beginning and an end. Defining the gene’s extremities…
Senescence is a state of enduring growth arrest triggered by sublethal cell damage. Given that…
Although long-read single-cell RNA isoform sequencing (scISO-Seq) can reveal alternative RNA splicing in individual cells,…