
INTERSTELLAR – A universal sequencing read interpreter
Massively parallel DNA sequencing has led to the rapid growth of highly multiplexed experiments in…
Massively parallel DNA sequencing has led to the rapid growth of highly multiplexed experiments in…
Pooled CRISPR screens coupled with single-cell RNA-sequencing have enabled systematic interrogation of gene function and…
Individual cells can assume a variety of molecular and phenotypic states and recent studies indicate…
Alternative polyadenylation (APA) is a major mechanism that increases transcriptional diversity and regulates mRNA abundance.…
In eukaryotic cells, miRNAs regulate a plethora of cellular functionalities ranging from cellular metabolisms, and…
Sophisticated methods to properly pre-process and analyze the increasing collection of single-cell RNA sequencing (scRNA-seq)…
Global alignment of complex pseudotime trajectories between different single-cell RNA-seq datasets is challenging, as existing…
A team led by researchers at the Wellcome-MRC Cambridge Stem Cell Institute has developed entropy…
Induced pluripotent stem cell (iPSC) derived cell types are increasingly employed as in vitro model…
With the advent of single-cell RNA sequencing (scRNA-seq), one major challenging is the so-called ‘dropout’…