scTsI – an effective two-stage imputation method for single-cell RNA-seq data
Single-cell RNA sequencing (scRNA-seq) has become an essential tool for understanding the diversity of cells…
Browsing: Other Tools
New statistical method identifies hidden gene programs linked to poor survival in aggressive pancreatic cancer
Researchers from UChicago built a statistical method to better understand the complexity of pancreatic cancer.…
DSRNAFold – enhanced RNA secondary structure prediction through integrative deep learning and structural context analysis
RNA molecules are essential players in our cells, involved in many crucial processes such as…
MEBOCOST – mapping metabolite-mediated intercellular communications using single-cell RNA-seq
Cell-to-cell communication is vital for our bodies to function properly. While scientists have long studied…
moPepGen – identification of non-canonical peptides from RNA-Seq data
Understanding the full complexity of proteins in cancer is a major challenge for scientists. Many…
Perturb-Multimodal – a platform for pooled genetic screens with imaging and sequencing in intact mammalian tissue
Scientists at the Howard Hughes Medical Institute have created a powerful new tool called Perturb-Multimodal,…
CADRES – precise detection of differential RNA editing sites across varied biological conditions
RNA editing is a crucial process that allows cells to make changes to RNA molecules…
VarRNA – variant calling from RNA-Seq data
Understanding how genetic changes drive cancer is one of the biggest challenges in biomedical research.…
Replicability of bulk RNA-Seq differential expression and enrichment analysis results for small cohort sizes
Researchers at the University of Bern explored a common issue in RNA sequencing (RNA-Seq) research—how…
miRglmm – a generalized linear mixed model of isomiR-level counts
MicroRNAs (miRNAs) are small but powerful molecules that play a crucial role in regulating gene…