scTensor detects many-to-many cell–cell interactions from single cell RNA-sequencing data
Complex biological systems are described as a multitude of cell-cell interactions (CCIs). Recent single-cell RNA-sequencing…
Browsing: Other Tools
sciCSR – infers B cell state transition and predicts class-switch recombination dynamics using single-cell transcriptomic data
Class-switch recombination (CSR) is an integral part of B cell maturation. Researchers at the University…
scDiffCom – a tool for differential analysis of cell–cell interactions from single-cell transcriptomics data
Dysregulation of intercellular communication is a hallmark of aging. To better quantify and explore changes…
Researchers develop RNA-Seq analysis tool for the safer design of gene editing
Scheme of safety evaluation by DANGER analysis. When off-target regions are affected by genome editing,…
BENGAL – benchmarking strategies for cross-species integration of single-cell RNA sequencing data
The growing number of available single-cell gene expression datasets from different species creates opportunities to…
Population-level integration of single-cell datasets enables multi-scale analysis across samples
The increasing amount of data recorded in medical research can only lead to scientific breakthroughs…
FWP – feature-weight based measurement of cancerous transcriptome using cohort-wide and sample-specific information
Identifying cancerous samples or cells using transcriptomic data is critical for cancer related basic research,…
DeepCCI – a deep learning framework for identifying cell–cell interactions from single-cell RNA sequencing data
Cell-cell interactions (CCIs) play critical roles in many biological processes such as cellular differentiation, tissue…
Deciphering RNA splicing logic with interpretable machine learning
Machine learning methods, particularly neural networks trained on large datasets, are transforming how scientists approach…
SCINPAS – single cell identification of novel PolyA sites
Alternative polyadenylation is a main driver of transcriptome diversity in mammals, generating transcript isoforms with…