CLIPreg – Constructing translational regulatory networks from CLIP-, Ribo- and RNA-seq
The creation and analysis of gene regulatory networks have been the focus of bioinformatics research…
Browsing: Publications
Microarray-based synthesis of large oligonucleotide pools as a source for distinct, non- random NGS barcodes
Researchers have demonstrated that, despite the intrinsically low raw accuracy of long-read sequencing technologies, multiplex…
Nuclear oligo hashing improves differential analysis of single-cell RNA-seq
Single-cell RNA sequencing (scRNA-seq) offers a high-resolution molecular view into complex tissues, but suffers from…
New single-cell RNA-sequencing method developed at IOB has potential to become universal tool of choice
A new single-cell RNA-sequencing protocol developed at IOB enables the detection of a significantly higher number of…
New database to “SpUR” on cancer research
Splicing (represented by the scissors) in noncoding parts of mRNA enhances its export from the…
Study tracking T-cell activation over time boosts search for immune disease treatments
Cells tracked through four points in time to map activation at molecular level In a…
Identification of protein isoforms using reference databases built from long and short read RNA-sequencing
Alternative splicing can lead to distinct protein isoforms. These can have different functions in specific…
Development and validation of an RNA-seq-based transcriptomic risk score for asthma
Recent progress in RNA sequencing (RNA-seq) allows us to explore whole-genome gene expression profiles and…
RNA sequencing reveals why people with COPD are more susceptible to COVID-19
Researchers from the Centenary Institute and the University of Technology Sydney have published the first…
RNA-Seq of the tumor microenvironment yielded an excellent correlation with immunohistochemistry and flow cytometry data
Understanding the tumor microenvironment (TME) and anti-tumor immune responses in gastric cancer are required for…