Narrowing numerous nascent RNA-sequencing strategies
How can we study RNA that is in the process of being synthesized? For over…
Browsing: Publications
Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics
Pulmonary fibrosis develops as a consequence of failed regeneration after injury. Analyzing mechanisms of regeneration…
Cell-type-specific genetic risk contributes to distinct stages of Alzheimer’s disease progression
Developing treatments for Alzheimer’s disease (AD) is difficult because complex underlying mechanisms drive different types…
How bacteria inhibit gene expression
From ASBMB Today by Meric Ozturk Bacteria adapt to environmental changes by regulating their metabolism.…
TsImpute – an accurate two-step imputation method for single-cell RNA-seq data
Single-cell RNA sequencing (scRNA-seq) technology has enabled discovering gene expression patterns at single cell resolution.…
DREEP – predicting drug response from single-cell expression profiles of tumours
Intra-tumour heterogeneity (ITH) presents a significant obstacle in formulating effective treatment strategies in clinical practice.…
Researchers discover new classes of RNA for learning and memory
Researchers from The University of Queensland have discovered a new way ribonucleic acid (RNA) impacts fear-related learning…
TECprobe-VL – variable length transcription elongation complex RNA structure probing
RNA begins to fold as it is transcribed by an RNA polymerase. Consequently, RNA folding…
Long-read scRNA-seq to become increasingly relevant in oncology and personalized medicine
Understanding the complex background of cancer requires genotype-phenotype information in single-cell resolution. Researchers at ETH…
Voltage-Seq – all-optical voltage imaging-guided postsynaptic single-cell transcriptome profiling
Neuronal pathways recruit large postsynaptic populations and maintain connections via distinct postsynaptic response types (PRTs).…