dRNA HybISS – high resolution spatial profiling of kidney injury and repair using RNA hybridization-based in situ sequencing
Understanding the intricate workings of the kidney and how it responds to injury is crucial…
Browsing: Workflows
A new exome capture-based RNA-sequencing assay for genome-wide identification and prioritization of clinically important fusions in pediatric tumors
Researchers at Children’s Hospital Los Angeles report on a new tool that effectively integrates data from…
Researchers use nanopore direct RNA sequencing to analyze viral RNA modifications
Modifications on viral RNAs (vRNAs), either genomic RNAs or RNA transcripts, have complex effects on…
New approach to single-cell RNA structure sequencing unveils biomarkers for human development and disease
Researchers from A*STAR’s Genome Institute of Singapore (GIS) have found an innovative approach to sequencing…
KARR-seq reveals cellular higher-order RNA structures and RNA–RNA interactions
RNA fate and function are affected by their structures and interactomes. However, how RNA and…
STIGMA – Single-cell tissue-specific gene prioritization using machine learning
Clinical exome and genome sequencing have revolutionized the understanding of human disease genetics. Yet many…
scSNV-seq – high-throughput phenotyping of single nucleotide variants by coupled single-cell genotyping and transcriptomics
CRISPR screens with single-cell transcriptomic readouts are a valuable tool to understand the effect of…
Zman-seq – time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma
Deciphering the cell-state transitions underlying immune adaptation across time is fundamental for advancing biology. Empirical in vivo…
MIT researchers can now track a cell’s RNA expression to investigate long-term processes like cancer progression or embryonic development
Sequencing all of the RNA in a cell can reveal a great deal of information…
RISER – biochemical-free enrichment or depletion of RNA classes in real-time during direct RNA sequencing
The heterogeneous composition of cellular transcriptomes poses a major challenge for detecting weakly expressed RNA…