Researchers find heart failure arises from mutations in numerous distinct genes
Microscope images of healthy heart tissue (left) and diseased heart tissue (right). Cell boundaries are…
Browsing: Publications
Transcriptome diversity in human tissues mapped with emerging long-read RNA sequencing technology
Expression of different forms of genes in human tissues has been mapped at unprecedented depth…
Significance analysis for clustering with single-cell RNA-sequencing data
Unsupervised clustering of single-cell RNA-sequencing data enables the identification and discovery of distinct cell populations.…
BacDrop – droplet-based single-cell RNA-seq reveals heterogeneity in bacterial populations and in response to antibiotic perturbation
Broad Institute researchers have developed BacDrop, a highly scalable technology for bacterial single-cell RNA sequencing…
Combi-seq – multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in single-cell droplets
Anti-cancer therapies often exhibit only short-term effects. Tumors typically develop drug resistance causing relapses that…
An application of RNA sequencing toward mRNA based nanotherapeutics against SARS-CoV-2 infections
Due to fast transmission and various circulating SARS-CoV-2 variants, a significant increase of coronavirus 2019…
See-N-Seq – RNA sequencing of target single cells identified by microscopy
Single cell RNA sequencing has the potential to elucidate transcriptional programs underlying key cellular phenotypes…
Circ-LocNet – a computational framework for circular RNA sub-cellular localization prediction
Circular ribonucleic acids (circRNAs) are novel non-coding RNAs that emanate from alternative splicing of precursor…
Single-cell RNA sequencing reveals CRISPR therapeutics can damage the genome
Researchers at Tel Aviv University caution: “The CRISPR genome editing method is very effective, but…
lncRNA sequencing study reveals set of deregulated genes in pancreatic cancer and points to potential therapeutic targets
Researchers analyzed the expression of long non-coding RNAs, the type that does not give rise…