DAESC – differential allelic expression using single-cell data
Differential allele-specific expression (ASE) is a powerful tool to study context-specific cis-regulation of gene expression.…
Browsing: Publications
FWP – feature-weight based measurement of cancerous transcriptome using cohort-wide and sample-specific information
Identifying cancerous samples or cells using transcriptomic data is critical for cancer related basic research,…
Single-cell transcriptomic atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology
Alzheimer’s disease (AD) is the most common cause of dementia worldwide, but the molecular and…
DeepCCI – a deep learning framework for identifying cell–cell interactions from single-cell RNA sequencing data
Cell-cell interactions (CCIs) play critical roles in many biological processes such as cellular differentiation, tissue…
Deciphering RNA splicing logic with interpretable machine learning
Machine learning methods, particularly neural networks trained on large datasets, are transforming how scientists approach…
STREAK – A supervised cell surface receptor abundance estimation strategy for single cell RNA-sequencing data using feature selection and thresholded gene set scoring
The accurate estimation of cell surface receptor abundance for single cell transcriptomics data is important…
New technique could help make precision medicine more widely available
Simple CUT&Tag adaptation gives information about genetic regulatory elements in formalin-fixed tumor samples Formalin-fixed, paraffin-embedded…
INVADEseq – invasion adhesion directed expression sequencing
Single-cell RNA sequencing (scRNAseq) technologies have been beneficial in revealing and describing cellular heterogeneity within…
Scientists reveal cellular changes unique to early Alzheimer’s disease
A study of brain tissue from living adults provides a rare look into the earliest…
Strand-specific RNA sequencing unveils wheat’s long non-coding RNAs : A leap in understanding grain development
Wheat is a global staple food and plays a pivotal role in the livelihoods of billions of people. Although long non-coding RNAs (lncRNAs)…