Measuring cell-to-cell expression variability in single-cell RNA-sequencing data
Single-cell RNA-sequencing (scRNA-seq) technologies enable the capture of gene expression heterogeneity and consequently facilitate the…
Browsing: Publications
3′ RNA-seq is superior to standard RNA-seq in cases of sparse data
The application of RNA-sequencing has led to numerous breakthroughs related to investigating gene expression levels…
Researchers develop circRNA-based early-detection method for pancreatic cancer
A simple blood test may pick up the emergence of this silent killer — usually…
How to build a cellular map of the musculoskeletal system
A single-cell resolution atlas of the human musculoskeletal system could be transformative to understanding and…
Single-nuclei characterization of pervasive transcriptional signatures across organs in response to COVID-19
Infection by coronavirus SARS-CoV2 is a severe and often deadly disease that has implications for…
BENGAL – benchmarking strategies for cross-species integration of single-cell RNA sequencing data
The growing number of available single-cell gene expression datasets from different species creates opportunities to…
Single-cell analysis of prenatal and postnatal human cortical development
Cortical development in humans is a meticulously regulated process that unfolds over months of prenatal…
The Human Breast Cell Atlas – world’s most comprehensive single-cell atlas of healthy breast tissue
The Human Breast Cell Atlas, recently published in Nature, is a landmark achievement for mammary biology…
Population-level integration of single-cell datasets enables multi-scale analysis across samples
The increasing amount of data recorded in medical research can only lead to scientific breakthroughs…
Bulk and single-cell RNA-seq data reveal what potentially causes a leukemia to become more aggressive
Scientists with City of Hope®, one of the largest cancer research and treatment organizations in…