MicroRNAs in immune cells help protect against metabolic defects in obesity
Vanderbilt researchers have demonstrated that a cluster of microRNAs — small pieces of RNA that…
Browsing: Publications
ScRNAPip – A systematic and dynamic pipeline for single-cell RNA sequencing analysis
With the advancement of sequencing technology, cell separation, and whole-genome amplification techniques, single cell technology…
COMPLETE-seq – noncoding RNA liquid biopsy platform improves cancer detection
A novel liquid biopsy technology developed by Assistant Professor of Biomolecular Engineering Daniel Kim’s lab…
Two distinct molecular faces of preeclampsia revealed by single-cell transcriptomics
Amit Zeisel, PhD and Ido Solt, MD and their research team at the Technion –…
sNucConv – a bulk RNA-seq deconvolution method trained on single-nucleus RNA-seq data to estimate cell-type composition
Deconvolution algorithms rely on single-cell RNA-sequencing (scRNA-seq) data applied onto bulk RNA-sequencing (bulk RNA-seq) to…
TimeTalk – decipher cell-cell communication from single-cell RNA-seq datasets
Early embryonic development is a dynamic process that relies on proper cell-cell communication to form…
Single-nucleus RNA sequencing identifies neuronal diversity and candidate mediators of circuit assembly
The superior colliculus (SC) is a sensorimotor structure in the midbrain that integrates input from…
Joint-snhmC-seq – simultaneously profile 5hmC and true 5mC in single cells
Oxidative modification of 5-methylcytosine (5mC) by ten-eleven translocation (TET) DNA dioxygenases generates 5-hydroxymethylcytosine (5hmC), the…
SLAM-Drop-seq reveals mRNA kinetic rates throughout the cell cycle
RNA abundance is tightly regulated in eukaryotic cells by modulating the kinetic rates of RNA…
scProjection – projecting RNA measurements onto single cell atlases to extract cell type-specific expression profiles
Multi-modal single cell RNA assays capture RNA content as well as other data modalities, such…