Deciphering RNA splicing logic with interpretable machine learning
Machine learning methods, particularly neural networks trained on large datasets, are transforming how scientists approach…
Browsing: Publications
STREAK – A supervised cell surface receptor abundance estimation strategy for single cell RNA-sequencing data using feature selection and thresholded gene set scoring
The accurate estimation of cell surface receptor abundance for single cell transcriptomics data is important…
New technique could help make precision medicine more widely available
Simple CUT&Tag adaptation gives information about genetic regulatory elements in formalin-fixed tumor samples Formalin-fixed, paraffin-embedded…
INVADEseq – invasion adhesion directed expression sequencing
Single-cell RNA sequencing (scRNAseq) technologies have been beneficial in revealing and describing cellular heterogeneity within…
Scientists reveal cellular changes unique to early Alzheimer’s disease
A study of brain tissue from living adults provides a rare look into the earliest…
Strand-specific RNA sequencing unveils wheat’s long non-coding RNAs : A leap in understanding grain development
Wheat is a global staple food and plays a pivotal role in the livelihoods of billions of people. Although long non-coding RNAs (lncRNAs)…
Comparative analysis of bioinformatics tools to characterize SARS-CoV-2 subgenomic RNAs
During the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), positive-sense genomic RNA and…
Single-cell RNA sequencing finds senescent immune cells promote lung tumor growth
Macrophages are a type of white blood cell that are among the body’s first line…
Establishment of a hybridoma sequencing pipeline for sequencing of antibody variable regions
The Neuroscience Monoclonal Antibody Sequencing Initiative (NeuroMabSeq) is a concerted effort to determine and make…
RNA-seq identifies stochastic RNA editing of synaptic genes in single neurons
Neurons stochastically generated up to eight different versions of a protein-regulating neurotransmitter release, which could…