TsImpute – an accurate two-step imputation method for single-cell RNA-seq data
Single-cell RNA sequencing (scRNA-seq) technology has enabled discovering gene expression patterns at single cell resolution.…
Browsing: Publications
DREEP – predicting drug response from single-cell expression profiles of tumours
Intra-tumour heterogeneity (ITH) presents a significant obstacle in formulating effective treatment strategies in clinical practice.…
Researchers discover new classes of RNA for learning and memory
Researchers from The University of Queensland have discovered a new way ribonucleic acid (RNA) impacts fear-related learning…
TECprobe-VL – variable length transcription elongation complex RNA structure probing
RNA begins to fold as it is transcribed by an RNA polymerase. Consequently, RNA folding…
Long-read scRNA-seq to become increasingly relevant in oncology and personalized medicine
Understanding the complex background of cancer requires genotype-phenotype information in single-cell resolution. Researchers at ETH…
Voltage-Seq – all-optical voltage imaging-guided postsynaptic single-cell transcriptome profiling
Neuronal pathways recruit large postsynaptic populations and maintain connections via distinct postsynaptic response types (PRTs).…
Researchers identify three genes associated with neurodevelopmental disorders
An international study group led by researchers of Children’s Hospital of Philadelphia (CHOP) have identified…
Fragment-Seq – local tissue microenvironments at single-cell resolution
Cells collectively determine biological functions by communicating with each other-both through direct physical contact and…
snHH-Seq – pan-cancer single-nucleus total RNA sequencing
Tumor heterogeneity and its drivers impair tumor progression and cancer therapy. Single-cell RNA sequencing is…
Optimised RNA extraction method unlocks tough tissues for aquaculture research
Researchers at the University of Edinburgh have optimised a protocol that allows previously tough-to-reach genetic…