scBayes – a Bayesian framework to study tumor subclone–specific expression by combining bulk DNA and single-cell RNA sequencing data
Genetic and gene expression heterogeneity is an essential hallmark of many tumors, allowing the cancer…
Genetic and gene expression heterogeneity is an essential hallmark of many tumors, allowing the cancer…
The advancement of single-cell sequencing technology has smoothed the ability to do biological studies at…
Single-cell RNA-seq analysis coupled with CRISPR-based perturbation has enabled the inference of gene regulatory networks…
Single-cell RNA sequencing (scRNA-seq) is a technique that has proven to be a powerful tool…
Single cell transcriptomics has recently seen a surge in popularity, leading to the need for…
Single-cell RNA sequencing (scRNA-seq) has revolutionized the study of gene expression at the individual cell…
Long-read RNA sequencing has emerged as a powerful tool for transcript discovery, even in well-annotated…
Intra-tumour heterogeneity (ITH) presents a significant obstacle in formulating effective treatment strategies in clinical practice.…
Double-stranded RNAs (dsRNAs) are potent triggers of innate immune responses upon recognition by cytosolic dsRNA…
Single-cell RNA sequencing (scRNA-seq) technologies have rapidly developed in recent years. The droplet-based single cell…