Plant single-cell/nucleus RNA-seq workflow
Single-cell transcriptomics technologies allow researchers to investigate how individual cells, in complex multicellular organisms, differentially…
Browsing: Workflows
scPolyA-seq – comprehensive mapping of alternative polyadenylation site usage and its dynamics at single-cell resolution
Alternative polyadenylation (APA) plays an important role in posttranscriptional gene regulation such as transcript stability…
DeepVelo – single-cell transcriptomic deep velocity field learning with neural ordinary differential equations
Recent advances in single-cell sequencing technologies have provided unprecedented opportunities to measure the gene expression…
Improved bacterial single-cell RNA-seq
Bulk RNA-sequencing technologies have provided invaluable insights into host and bacterial gene expression and associated…
RNAmp – directly measure widespread hypertranscription in aggressive human cancers
Cancers are often defined by the dysregulation of specific transcriptional programs; however, the importance of…
SMS-seq – long-read single-molecule RNA structure sequencing using nanopore
RNA molecules can form secondary and tertiary structures that can regulate their localization and function.…
First use of transcriptomics as a blood test to measure RNA levels in patients with long-term Lyme disease
Researchers at the Icahn School of Medicine at Mount Sinai in New York have identified…
RNA sequencing from FFPE tissues for spatial gene expression analysis
Spatial transcriptome analysis of formalin-fixed paraffin-embedded (FFPE) tissues using RNA-sequencing (RNA-seq) provides interactive information on…
rG4-seq 2.0 – enhanced transcriptome-wide RNA G-quadruplex sequencing for low RNA input samples
RNA G-quadruplexes (rG4s) are non-canonical structural motifs that have diverse functional and regulatory roles, for…
Second-generation single-cell sequencing resolves plant specific cell type subpopulations
While recent advances in plant single-cell RNA sequencing (scRNA-seq) have made numerous strides in identifying…