VarRNA – variant calling from RNA-Seq data
Understanding how genetic changes drive cancer is one of the biggest challenges in biomedical research.…
Browsing: Splicing and Junction Mapping
DeepSAP – improved RNA-seq alignment by integrating transcriptome guidance with transformer-based splice junction scoring
RNA sequencing (RNA-seq) has opened up new frontiers in our understanding of gene expression and…
MrHAMER2 – high-accuracy long-read RNA sequencing to decode isoform-specific variation in viral transcripts during latency
The ability of HIV to hide in a latent state, lying dormant within host cells,…
New AI tool pinpoints gene splicing with unmatched precision
A recent innovation from Johns Hopkins researchers enables deeper insights into gene function and disease-linked…
scASfind – mining alternative splicing patterns in scRNA-seq data
Single-cell RNA sequencing (scRNA-seq) is a powerful tool researchers use to understand how genes work…
FLAIR2 – detecting haplotype-specific transcript variation in long reads
RNA sequencing (RNA-seq) has transformed our ability to study RNA, the molecule that plays a…
rMATS-turbo – an efficient and flexible computational tool for alternative splicing analysis of large-scale RNA-seq data
The process of alternative splicing adds a layer of complexity to the way genetic information…
Nucleotide-level distance metrics to quantify alternative splicing implemented in TranD
Advances in affordable transcriptome sequencing combined with better exon and gene prediction has motivated many…
betAS – intuitive analysis and visualisation of differential alternative splicing using beta distributions
Next generation RNA sequencing allows alternative splicing (AS) quantification with unprecedented resolution, with the relative…
SpliceWiz – interactive analysis and visualization of alternative splicing in R
Alternative splicing (AS) is a crucial mechanism for regulating gene expression and isoform diversity in…