rMATS-turbo – an efficient and flexible computational tool for alternative splicing analysis of large-scale RNA-seq data
The process of alternative splicing adds a layer of complexity to the way genetic information…
Browsing: Splicing and Junction Mapping
Nucleotide-level distance metrics to quantify alternative splicing implemented in TranD
Advances in affordable transcriptome sequencing combined with better exon and gene prediction has motivated many…
betAS – intuitive analysis and visualisation of differential alternative splicing using beta distributions
Next generation RNA sequencing allows alternative splicing (AS) quantification with unprecedented resolution, with the relative…
SpliceWiz – interactive analysis and visualization of alternative splicing in R
Alternative splicing (AS) is a crucial mechanism for regulating gene expression and isoform diversity in…
RedRibbon – A new rank–rank hypergeometric overlap for gene and transcript expression signatures
High-throughput omics technologies have generated a wealth of large protein, gene, and transcript datasets that…
RiboSplitter – prediction of alternative pre-mRNA splicing outcomes
To understand the biological impact of alternative pre-mRNA splicing, it is vital to know which…
MkcDBGAS – a reference-free approach to identify comprehensive alternative splicing events in a transcriptome
Alternative splicing (AS) is an essential post-transcriptional mechanism that regulates many biological processes. However, identifying…
Deciphering RNA splicing logic with interpretable machine learning
Machine learning methods, particularly neural networks trained on large datasets, are transforming how scientists approach…
New algorithm six times more reliable at predicting defective RNA
So far, it has not been possible to explain the causes of around half of…
Alternative splicing analysis benchmark with DICAST
Alternative splicing is a major contributor to transcriptome and proteome diversity in health and disease.…