Mutant KRAS signaling drives alternative splicing in lung cancer cells
What eventually becomes a graduate student’s PhD thesis work is rarely the project they initially…
Browsing: Publications
Single cell RNA-sequencing identifies cause for loss of smell in long COVID patients
As the pandemic continues, millions of people in the U.S. are facing long COVID, a…
ESPRESSO – robust discovery and quantification of transcript isoforms from error-prone long-read RNA-seq data
Long-read RNA sequencing (RNA-seq) holds great potential for characterizing transcriptome variation and full-length transcript isoforms,…
Single-cell RNA sequencing reveals how Huntington’s disease affects different neurons
A new study identifies cells that are the most vulnerable within a brain structure involved…
PAIso-seq reveals how poly(A)-tail-mediated remodeling of maternal mRNA controls start of life
Human development starts from the fertilization of a fully matured oocyte. Oocyte maturation, fertilization, and…
RNA sequencing study reveals new molecular associations with obesity
New research from the Department of Biomedical Informatics (DBMI) at the University of Colorado School of Medicine has identified…
A new sequencing technique achieves high-quality results from small volumes of frozen tumor specimens archived in biobanks
Columbia researchers invent a technique to study cancer tissues archived in biobanks, increasing the number…
scRNAseq_KNIME workflow – a customizable, locally executable, interactive and automated KNIME workflow for single-cell RNA seq
Single-cell RNA sequencing (scRNA-seq) is nowadays widely used to measure gene expression in individual cells,…
Single-cell transcriptomics of peripheral blood in the aging mouse
Compositional and transcriptional changes in the hematopoietic system have been used as biomarkers of immunosenescence…
Researchers produce first-ever toolkit for RNA sequencing analysis using a ‘pantranscriptome’
Analyzing a person’s gene expression requires mapping their RNA landscape to a standard reference to…