PRO-IP-seq – tracks molecular modifications of engaged Pol II complexes at nucleotide resolution
RNA Polymerase II (Pol II) is a multi-subunit complex that undergoes covalent modifications as transcription…
Browsing: Publications
Transcriptome software results show significant variation among different commercial pipelines
Researchers at New Mexico State University have been documenting the biological responses to low levels…
scDiffCom – a tool for differential analysis of cell–cell interactions from single-cell transcriptomics data
Dysregulation of intercellular communication is a hallmark of aging. To better quantify and explore changes…
DiSignAtlas – an atlas of human and mouse disease signatures based on bulk and single-cell transcriptomics
Molecular signatures are usually sets of biomolecules that can serve as diagnostic, prognostic, predictive, or…
RNA sequencing reveals high metabolism is an early sign of Alzheimer’s disease
An early phase in the process of developing Alzheimer’s disease is a metabolic increase in…
Hidden way for us to feel touch uncovered by single-cell RNA sequencing
Imperial researchers have discovered a hidden mechanism within hair follicles that allow us to feel…
New method tracks how brain cells age
Hospital nurseries routinely place soft bands around the tiny wrists of newborns that hold important…
Benchmarking algorithms for joint integration of unpaired and paired single-cell RNA-seq and ATAC-seq data
Single-cell RNA-sequencing (scRNA-seq) measures gene expression in single cells, while single-nucleus ATAC-sequencing (snATAC-seq) quantifies chromatin…
Single-cell RNA sequencing details immune system’s role in metabolic disease
Researchers at Vanderbilt University Medical Center have published the largest single-site adipose tissue atlas known…
MkcDBGAS – a reference-free approach to identify comprehensive alternative splicing events in a transcriptome
Alternative splicing (AS) is an essential post-transcriptional mechanism that regulates many biological processes. However, identifying…