Internal and external normalization of nascent RNA sequencing run-on experiments
In experiments with significant perturbations to transcription, nascent RNA sequencing protocols are dependent on external…
Browsing: Publications
SinCMat – A single-cell-based method for predicting functional maturation transcription factors
A major goal of regenerative medicine is to generate tissue-specific mature and functional cells. However,…
Single-cell RNA sequencing reveals CD4+ T cell patterns linked to autoimmune disorders
Researchers from Osaka University find characteristic changes in CD4+ T cell categories and gene programs…
The hidden identity of leukemia revealed by single-cell RNA sequencing
Researchers from Tokyo Medical and Dental University (TMDU) use various technologies to better characterize a…
NIH-supported researchers create single-cell atlas of the placenta during term labor
An atlas revealing the activity of individual placental cells during childbirth offers insight on what…
RNA-Seq reveals EBV-specific T-cells play key role in development of multiple sclerosis
The body’s immune response to Epstein-Barr virus (EBV) may play a role in causing damage…
Bifrost Biosystems launches with novel optical pooled screening technology to power efficient discovery
Bifrost Biosystems announced its launch with a vision to power efficient drug discovery through its…
RISER – biochemical-free enrichment or depletion of RNA classes in real-time during direct RNA sequencing
The heterogeneous composition of cellular transcriptomes poses a major challenge for detecting weakly expressed RNA…
SLiPiR-seq – terminal modifications independent cell-free RNA sequencing
Cell-free RNAs (cfRNAs) offer an opportunity to detect diseases from a transcriptomic perspective, however, existing…
Could the optimal pipeline be predicted for a given scRNA-Seq dataset?
The advent of single-cell RNA-sequencing (scRNA-seq) has driven significant computational methods development for all steps…