New method tags cells with location coordinates for single-cell studies
The technique, called Slide-tags, allows scientists to map the location of cells within tissues in…
Browsing: Publications
RedRibbon – A new rank–rank hypergeometric overlap for gene and transcript expression signatures
High-throughput omics technologies have generated a wealth of large protein, gene, and transcript datasets that…
DeconV – probabilistic cell type deconvolution from bulk rna-sequencing data
Bulk RNA-Seq remains a widely adopted technique to profile gene expression, primarily due to the…
SQANTI-SIM – a simulator of controlled transcript novelty for lrRNA-seq benchmark
Long-read RNA sequencing has emerged as a powerful tool for transcript discovery, even in well-annotated…
iRIL-seq – In vivo RNA interactome profiling
In a study published in Nature Communications, Prof. CHAO Yanjie’s group at the Institute of Shanghai Institute of…
Wistar scientists use RNA-Seq to identify esophageal cancer biomarkers
Wistar scientists have developed a new tool that can help identify cancer-associated microbes by using…
Narrowing numerous nascent RNA-sequencing strategies
How can we study RNA that is in the process of being synthesized? For over…
Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics
Pulmonary fibrosis develops as a consequence of failed regeneration after injury. Analyzing mechanisms of regeneration…
Cell-type-specific genetic risk contributes to distinct stages of Alzheimer’s disease progression
Developing treatments for Alzheimer’s disease (AD) is difficult because complex underlying mechanisms drive different types…
How bacteria inhibit gene expression
From ASBMB Today by Meric Ozturk Bacteria adapt to environmental changes by regulating their metabolism.…