
PUREE – accurate pan-cancer tumor purity estimation from gene expression data
Tumors are complex masses composed of malignant and non-malignant cells. Variation in tumor purity (proportion…
Tumors are complex masses composed of malignant and non-malignant cells. Variation in tumor purity (proportion…
Established prognostic tests based on limited numbers of transcripts can identify high-risk breast cancer patients…
Characterizing the topology of gene regulatory networks (GRNs) is a fundamental problem in systems biology.…
RNA velocity provides an approach for inferring cellular state transitions from single-cell RNA sequencing (scRNA-seq)…
Biomedical researchers use alignments produced by BLAST (Basic Local Alignment Search Tool) to categorize their…
Doublets formed during single-cell RNA sequencing (scRNA-seq) severely affect downstream studies, such as differentially expressed…
Single-cell RNA sequencing has been instrumental in uncovering cellular spatiotemporal context. This task is challenging…
Single-cell multi-omics (scMulti-omics) allows the quantification of multiple modalities simultaneously to capture the intricacy of…
The advance in single-cell RNA sequencing technology has enhanced the analysis of cell development by…
Amplicon sequencing is an effective and increasingly applied method for studying viral communities in the…