Base-resolution sequencing methods for whole-transcriptome quantification of mRNA modifications
RNA molecules are not merely a combination of four bases of A, C, G, and…
Browsing: Review Publications
Breakthroughs in RNA sequencing lead to rapid expansion of the human non-coding RNA catalog
Scientists have been trying to identify every gene in the human genome since the initial…
Time is right to develop a consensus Human Skin Cell Atlas, according to leading dermatology experts
As a single organ, our skin is able to perform a broad repertoire of vital…
The dawn of spatial omics
BACKGROUND Just as single-cell sequencing has revolutionized many fields of biology, spatial “omics,” in which…
The promise of single-cell rna sequencing to redefine the understanding of Crohn’s Disease fibrosis mechanisms
Crohn’s disease (CD) is a chronic inflammatory bowel disease with a high prevalence throughout the…
Applications of single-cell RNA sequencing in drug discovery and development
Single-cell technologies, particularly single-cell RNA sequencing (scRNA-seq) methods, together with associated computational tools and the…
Methods and applications for single-cell and spatial multi-omics
The joint analysis of the genome, epigenome, transcriptome, proteome and/or metabolome from single cells is…
Improving diagnosis of genetic diseases with RNA sequencing
The use of next-generation sequencing (NGS) has simplified the diagnosis of human genetic disorders. Since…
The evolution of single-cell RNA sequencing technology and application: progress and perspectives
As an emerging sequencing technology, single-cell RNA sequencing (scRNA-Seq) has become a powerful tool for…
An introduction to nanopore sequencing
There has been significant progress made in the field of nanopore biosensor development and sequencing…