Orgo-Seq – integration of single-cell and bulk transcriptomic data to identify cell type specific-driver genes
Cerebral organoids can be used to gain insights into cell type specific processes perturbed by…
Browsing: Publications
Researchers used single-cell sequencing tool Perturb-seq on every human gene, linking each to its job in the cell
The Human Genome Project was an ambitious initiative to sequence every piece of human DNA.…
Stem-cell models reveal glaucoma secrets
Stem cell models of the retina and optical nerve have been used to identify previously…
Monash researchers use scRNA-Seq to uncover genetic underpinnings of the immune system
Researchers from Monash University have demonstrated how genetic variation influences the expression of genes that…
A systematic evaluation of parameters in RNA bisulfite sequencing data generation and analysis
The presence of 5-methylcytosine (m5C) in RNA molecules has been known for decades and its…
New gold-standard quality control tool for RNA sequencing in single cells
Researchers at Karolinska Institutet are introducing a new gold standard quality-control tool for counting of…
Integration of single-cell RNA sequencing, antigen-receptor sequencing, and spatial transcriptomics to reconstruct the immune system’s development through time and space
The human immune system develops across several anatomical sites throughout gestation. Immune cells differentiate initially…
scAmpi – A versatile pipeline for single-cell RNA-seq analysis from basics to clinics
Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful technique to decipher tissue composition at…
RNA-MuTect-WMN – Estimating tumor mutational burden from RNA-sequencing without a matched-normal sample
Detection of somatic mutations using patients sequencing data has many clinical applications, including the identification…
CLIPreg – Constructing translational regulatory networks from CLIP-, Ribo- and RNA-seq
The creation and analysis of gene regulatory networks have been the focus of bioinformatics research…