A spatially resolved atlas of the human lung characterizes a gland-associated immune niche
Single-cell transcriptomics has allowed unprecedented resolution of cell types/states in the human lung, but their…
Browsing: Publications
DLNLRR – non-negative low-rank representation based on dictionary learning for single-cell RNA-sequencing data analysis
In the analysis of single-cell RNA-sequencing (scRNA-seq) data, how to effectively and accurately identify cell…
CHOP and NJIT researchers develop new tool for studying multiple characteristics of a single cell
Researchers from Children’s Hospital of Philadelphia (CHOP) and New Jersey Institute of Technology (NJIT) developed new software…
CaRPool-seq – combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq
Pooled CRISPR screens coupled with single-cell RNA-sequencing have enabled systematic interrogation of gene function and…
Single-nucleus RNA-sequencing and spatial transcriptomics profiling reveal how cancer cells evade targeted therapy
UCSF Researchers Identify the Cellular Source of Recurrent Glioma Microscopy of glioblastoma cells invading a…
Merging short and stranded long reads improves transcript assembly
Long-read RNA sequencing has arisen as a counterpart to short-read sequencing, with the potential to…
The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation
The application of single-cell RNA sequencing in COVID-19 research has greatly improved our understanding of…
Assessing the nucleotide-level impact of spaceflight stress using RNA-sequencing data
Understanding the effects of space radiation and microgravity on DNA integrity is critical to assess…
Single-cell study brings prostate tumors into focus and highlights potential treatment target
Treatments targeting the androgen receptor have extended the lives of people with advanced prostate cancer.…
ENTER-seq – multiplexed enumeration of antigen specificities, TCR clonality, cell type, and states of individual T cells
Cells communicate with each other via receptor-ligand interactions. Researchers at Stanford University have developed lentiviral-mediated…