dd-scCNV Seq – digital microfluidics-based digital counting of single-cell copy number variation
Single-cell copy number variations (CNVs), major dynamic changes in humans, result in differential levels of…
Browsing: Publications
cellsnake – a user-friendly tool for single cell RNA sequencing analysis
Single-cell RNA sequencing (scRNA-seq) provides high-resolution transcriptome data to understand the heterogeneity of cell populations…
kimma – flexible linear mixed effects modeling with kinship covariance for RNA-seq data
The identification of differentially expressed genes (DEGs) from transcriptomic datasets is a major avenue of…
scEC&T-seq – parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells
Extrachromosomal DNAs (ecDNAs) are common in cancer, but many questions about their origin, structural dynamics…
Colon cancer microbiome reconstruction from human RNA sequencing data
The association between microbes and cancer has been reported repeatedly; however, it is not clear…
Researchers use RATESeq to measure the rate of both transcription and breakdown of RNA molecules in human disease
Every cell in our body is able to turn genes (DNA) on or off, producing…
Systematic evaluation of the two main blood-based RNA-seq approaches for Mendelian disease diagnosis
As an adjunct to diagnostic exome sequencing and whole-genome sequencing, RNA sequencing (RNA-seq) has been…
Nano-DMS-MaP – isoform-specific RNA structure determination
Genome-wide measurements of RNA structure can be obtained using reagents that react with unpaired bases,…
An RNA-Seq assay for classifying cancers of unknown primary origin
Cancers assume a variety of distinct histologies, and may originate from a myriad of sites…
Transformation of alignment files improves performance of variant callers for long-read RNA sequencing data
Long-read RNA sequencing (lrRNA-seq) produces detailed information about full-length transcripts, including novel and sample-specific isoforms.…