scSemiAAE – a semi-supervised clustering model for single-cell RNA-seq data
Single-cell RNA sequencing (scRNA-seq) strives to capture cellular diversity with higher resolution than bulk RNA…
Browsing: Publications
scMEB – a fast and clustering-independent method for detecting differentially expressed genes in single-cell RNA-seq data
Cell clustering is a prerequisite for identifying differentially expressed genes (DEGs) in single-cell RNA sequencing…
Researchers weave deeper understanding of diverse ancestry and gene expression
Novel research from the Department of Biomedical Informatics examines the relationship between complex traits and…
ExpressAnalyst – a unified platform for RNA-sequencing analysis in non-model species
The increasing application of RNA sequencing to study non-model species demands easy-to-use and efficient bioinformatics…
Celloscope – a probabilistic model for marker-gene-driven cell type deconvolution in spatial transcriptomics data
Spatial transcriptomics maps gene expression across tissues, posing the challenge of determining the spatial arrangement…
gExcite – a start-to-end framework for single-cell gene expression, hashing, and antibody analysis
Recently, CITE-seq emerged as a multimodal single-cell technology capturing gene expression and surface protein information…
RNA-Seq reveals orchids’ ability to grow on other plants independently evolved multiple times
New transcriptome data sets clarifies the evolutionary relationships among orchids and reveals that the plant’s…
New RNA sequencing method reveals bacterial reaction to antibiotics in five minutes
Researchers at Karolinska Institutet have developed a molecular method able to detect whether or not…
Single-cell spatial analysis identifies regulators of brain tumor–initiating cells
Glioblastomas (GBM) are aggressive brain tumors with extensive intratumoral heterogeneity that contributes to treatment resistance.…
tiny-count – a counting tool for hierarchical classification and quantification of small RNA-seq reads with single-nucleotide precision
Researchers at Colorado State University have developed tiny-count, a highly flexible counting tool that allows for…