GRAB-ALL – a high-throughput pipeline for DNA/RNA/small RNA purification from tissue samples for sequencing
High-throughput total nucleic acid (TNA) purification methods based on solid-phase reversible immobilization (SPRI) beads produce…
Browsing: Publications
contrastiveVI – isolating salient variations of interest in single-cell data
Single-cell datasets are routinely collected to investigate changes in cellular state between control cells and…
Dana-Farber AI-model predicts primary source of cancer using gene sequencing data
Researchers at Dana-Farber Cancer Institute have created an AI-based tool that uses tumor gene sequencing…
Nanopore technology achieves breakthrough in protein variant detection
A team of scientists led by the University of Oxford have achieved a significant breakthrough…
Single-cell sequencing reveals the landscape of the human brain metastatic microenvironment
Brain metastases is the most common intracranial tumor and account for approximately 20% of all…
Single-cell RNA sequencing identifies cause of inner-ear bone loss
Researchers from Osaka University show that the possible cause of local bone erosion in cholesteatomas…
The ENCODE4 long-read RNA-seq collection reveals distinct classes of transcript structure diversity
The majority of mammalian genes encode multiple transcript isoforms that result from differential promoter use,…
Single-nuclei RNA sequencing detects gene splicing defect known as “cryptic exons” in ALS
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are devastating neurodegenerative diseases with mean survival…
New sequencing methods reveal the RNA secrets of extreme microorganisms
Regensburg researchers decode the step-by-step ribosome biosynthesis in archaea. Archaea are microscopic life forms that…
Researchers develop an innovative approach to classify metastases in patients with colorectal cancer from mRNA and miRNA expression profiles
Once cancer spreads to different parts of the body (known as metastasis), it is more…