Researchers use nanopore direct RNA sequencing to analyze viral RNA modifications
Modifications on viral RNAs (vRNAs), either genomic RNAs or RNA transcripts, have complex effects on…
Browsing: Publications
A single cell RNAseq benchmark experiment embedding “controlled” cancer heterogeneity
Single-cell RNA sequencing (scRNA-seq) has emerged as a vital tool in tumour research, enabling the…
New research improves accuracy of molecular quantification in high throughput RNA sequencing
A team at NDORMS has developed a new approach to significantly improve the accuracy of…
Robust detection of clinically relevant features in single-cell RNA profiles of patient-matched fresh and FFPE lung cancer tissue
Single-cell transcriptional profiling reveals cell heterogeneity and clinically relevant traits in intra-operatively collected patient-derived tissue.…
A reliable transcriptomic risk-score applicable to FFPE biopsies improves outcome prediction in localized prostate cancer
Clinical manifestation of prostate cancer (PCa) is highly variable. Aggressive tumors require radical treatment while…
Protein production glitches in Huntington’s disease revealed by RNA sequencing
DNA, often thought of as “the blueprint of life”, contains instructions for building proteins that…
RNA sequencing analysis may hold the key to more accurate diagnosis and targeted treatment of leukemia
Pilot study by Children’s Hospital Los Angeles and City of Hope proposes a promising global,…
betAS – intuitive analysis and visualisation of differential alternative splicing using beta distributions
Next generation RNA sequencing allows alternative splicing (AS) quantification with unprecedented resolution, with the relative…
Double stranded RNA sequencing reveals a third RNA virus linage in extreme environments
Image by kan_khampanya/Shutterstock A research group led by University of Tsukuba has discovered a novel…
CAP-RNAseq – an integrated pipeline for functional annotation and prioritization of co-expression clusters
Cluster analysis is one of the most widely used exploratory methods for visualization and grouping…