Cellograph – a semi-supervised approach to analyzing multi-condition single-cell RNA-sequencing data using graph neural networks
With the growing number of single-cell datasets collected under more complex experimental conditions, there is…
Browsing: Publications
Single-cell analysis of stromal cells may help predict prostate cancer metastasis
Non-cancerous cells called stromal cells, which are found in and around prostate tumors, may be…
KARR-seq reveals cellular higher-order RNA structures and RNA–RNA interactions
RNA fate and function are affected by their structures and interactomes. However, how RNA and…
STIGMA – Single-cell tissue-specific gene prioritization using machine learning
Clinical exome and genome sequencing have revolutionized the understanding of human disease genetics. Yet many…
scSNV-seq – high-throughput phenotyping of single nucleotide variants by coupled single-cell genotyping and transcriptomics
CRISPR screens with single-cell transcriptomic readouts are a valuable tool to understand the effect of…
Zman-seq – time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma
Deciphering the cell-state transitions underlying immune adaptation across time is fundamental for advancing biology. Empirical in vivo…
Internal and external normalization of nascent RNA sequencing run-on experiments
In experiments with significant perturbations to transcription, nascent RNA sequencing protocols are dependent on external…
SinCMat – A single-cell-based method for predicting functional maturation transcription factors
A major goal of regenerative medicine is to generate tissue-specific mature and functional cells. However,…
Single-cell RNA sequencing reveals CD4+ T cell patterns linked to autoimmune disorders
Researchers from Osaka University find characteristic changes in CD4+ T cell categories and gene programs…
The hidden identity of leukemia revealed by single-cell RNA sequencing
Researchers from Tokyo Medical and Dental University (TMDU) use various technologies to better characterize a…