
CAPITAL – alignment of single-cell trajectory trees
Global alignment of complex pseudotime trajectories between different single-cell RNA-seq datasets is challenging, as existing…
Global alignment of complex pseudotime trajectories between different single-cell RNA-seq datasets is challenging, as existing…
A team led by researchers at the Wellcome-MRC Cambridge Stem Cell Institute has developed entropy…
Induced pluripotent stem cell (iPSC) derived cell types are increasingly employed as in vitro model…
With the advent of single-cell RNA sequencing (scRNA-seq), one major challenging is the so-called ‘dropout’…
Single-cell RNA sequencing (scRNA-seq) data contain rich information at the gene, transcript, and nucleotide levels.…
Genetic and epigenetic biological studies often combine different types of experiments and multiple conditions. While…
With the upcoming of affordable Next-Generation Sequencing technologies, the number of known non-protein coding RNAs…
Single-cell RNA-sequencing (scRNA-seq) is a recent high-throughput technique that can measure gene expression, reveal cell…
Alternative cleavage and polyadenylation (APA) contributes to the diversity of mRNA 3′ ends, affecting post-transcriptional…
RNA-sequencing of plant material allows for hypothesis-free detection of multiple viruses simultaneously. This methodology relies…