Unraveling the timeline of gene expression – a pseudotemporal trajectory analysis of single-cell RNA sequencing data
Single-cell RNA sequencing (scRNA-seq) technologies have rapidly developed in recent years. The droplet-based single cell…
Browsing: Analysis Pipelines
RiboSplitter – prediction of alternative pre-mRNA splicing outcomes
To understand the biological impact of alternative pre-mRNA splicing, it is vital to know which…
RiboGalaxy – A Galaxy-based web platform for ribosome profiling data processing – 2023 Update
Ribosome profiling (Ribo-Seq) captures a “snapshot” of ribosomes’ locations at the entire transcriptome of a…
scTensor detects many-to-many cell–cell interactions from single cell RNA-sequencing data
Complex biological systems are described as a multitude of cell-cell interactions (CCIs). Recent single-cell RNA-sequencing…
sciCSR – infers B cell state transition and predicts class-switch recombination dynamics using single-cell transcriptomic data
Class-switch recombination (CSR) is an integral part of B cell maturation. Researchers at the University…
scDiffCom – a tool for differential analysis of cell–cell interactions from single-cell transcriptomics data
Dysregulation of intercellular communication is a hallmark of aging. To better quantify and explore changes…
New method tracks how brain cells age
Hospital nurseries routinely place soft bands around the tiny wrists of newborns that hold important…
Researchers develop RNA-Seq analysis tool for the safer design of gene editing
Scheme of safety evaluation by DANGER analysis. When off-target regions are affected by genome editing,…
GCFG – combining global-constrained concept factorization and a regularized gaussian graphical model for clustering single-cell RNA-Seq data
Single-cell RNA sequencing technology is one of the most cost-effective ways to uncover transcriptomic heterogeneity.…
Population-level integration of single-cell datasets enables multi-scale analysis across samples
The increasing amount of data recorded in medical research can only lead to scientific breakthroughs…