sciCSR – infers B cell state transition and predicts class-switch recombination dynamics using single-cell transcriptomic data
Class-switch recombination (CSR) is an integral part of B cell maturation. Researchers at the University…
Browsing: Analysis Pipelines
scDiffCom – a tool for differential analysis of cell–cell interactions from single-cell transcriptomics data
Dysregulation of intercellular communication is a hallmark of aging. To better quantify and explore changes…
New method tracks how brain cells age
Hospital nurseries routinely place soft bands around the tiny wrists of newborns that hold important…
Researchers develop RNA-Seq analysis tool for the safer design of gene editing
Scheme of safety evaluation by DANGER analysis. When off-target regions are affected by genome editing,…
GCFG – combining global-constrained concept factorization and a regularized gaussian graphical model for clustering single-cell RNA-Seq data
Single-cell RNA sequencing technology is one of the most cost-effective ways to uncover transcriptomic heterogeneity.…
Population-level integration of single-cell datasets enables multi-scale analysis across samples
The increasing amount of data recorded in medical research can only lead to scientific breakthroughs…
SCINPAS – single cell identification of novel PolyA sites
Alternative polyadenylation is a main driver of transcriptome diversity in mammals, generating transcript isoforms with…
mitoSplitter – A mitochondrial variants-based method for efficient demultiplexing of pooled single-cell RNA-seq
Single-cell RNA-seq (scRNA-seq) analysis of multiple samples separately can be costly and lead to batch…
SAHMI – denoising sparse microbial signals from single-cell sequencing of mammalian host tissues
Existing genomic sequencing data can be used to study host–microbiome ecosystems; however, distinguishing signals that…
A cross-cohort computational framework to trace tumor tissue-of-origin based on RNA sequencing
Carcinoma of unknown primary (CUP) is a type of metastatic cancer with tissue-of-origin (TOO) unidentifiable…