The impact of RNA degradation on next-generation sequencing transcriptome data
RNA sequencing is an innovative technology to study transcriptomes in both biological and clinical research.…
Browsing: Publications
Wastewater RNA sequencing provides early detection of SARS-CoV-2 virus and its variants
Writing in the July 7, 2022 online issue of Nature, scientists and physicians at University of…
ConfoundR – stop biological misinterpretation of transcriptional signatures
Precise mechanism-based gene expression signatures (GESs) have been developed in appropriate in vitro and in…
Novel approach combines a T-cell “barcode” with single-cell RNA sequencing to enhance CAR T–cell therapy
Scientists at St. Jude Children’s Research Hospital have developed a method that may be able to improve…
New method facilitates identification of cell-type specific genes in single-cell data
The thousands of cells in a biological sample are all different and can be analyzed…
A comprehensive analytical protocol to interrogate multiple single-cell RNA-seq datasets with SingCellaR
Single-cell RNA sequencing has led to unprecedented levels of data complexity. Although several computational platforms…
scONE-seq – simultaneous single-cell transcriptome and genome profiling in a one-tube reaction
Genomic and transcriptomic heterogeneity both play important roles in normal cellular function as well as…
New sequencing technique (SENT-seq) could accelerate and improve mRNA therapies
Therapeutics based on messenger RNA, or mRNA, can potentially treat a wide range of maladies,…
VASA-seq – high-throughput total RNA sequencing in single cells
Most methods for single-cell transcriptome sequencing amplify the termini of polyadenylated transcripts, capturing only a…
ResPAN – a powerful batch correction model for scRNA-seq data through residual adversarial networks
With the advancement of technology, we can generate and access large-scale, high dimensional and diverse…