RNA sequencing reveals changed gene expression after heart surgery extends cardiomyocyte regeneration
While lower vertebrates can repair their adult hearts after a heart attack, mammals — including…
Browsing: Publications
Amphioxus sequencing gives insight on vertebrate evolution
Vertebrate evolution was accompanied by two rounds of whole genome duplication followed by functional divergence…
A workflow for high throughput SARS-CoV-2 variant analysis via NGS with molecular barcodes
The identification of SARS-CoV-2 variants across the globe and their implications on the outspread of…
Single-cell gene expression analyses of human cerebrovascular cells can help reveal new drug targets for Huntington’s disease and other neurodegenerative diseases
In vessels of people with Huntington’s disease (right image) researchers saw much higher indications of…
RNA-Seq-Pop – Exploiting the sequence in RNA-Seq – a Snakemake workflow
Researchers at the Liverpool School of Tropical Medicine have developed a reproducible and scalable Snakemake…
PASTE – alignment and integration of spatial transcriptomics data
Spatial transcriptomics (ST) measures mRNA expression across thousands of spots from a tissue slice while…
Single-cell RNA sequencing reveals mechanism that causes both inflammation and immunosuppression in tumors
If cancerous cells started wreaking havoc in your body, like terrorists in a building, your…
Mount Sinai researchers discover genes that predict good response to blood cancer therapy
Patients whose multiple myeloma has three-gene signature are likely to benefit Mount Sinai researchers have…
Single-cell RNA sequencing reveals breast cancer biomarkers of response
Neoadjuvant chemotherapy (NAC) is the standard of care for many patients with breast cancer. Biomarkers of…
Single-cell atlas of drug treatments in a mouse model of diabetic kidney disease
Diabetic kidney disease (DKD) occurs in ∼40% of patients with diabetes and causes kidney failure,…