New sequencing technique (SENT-seq) could accelerate and improve mRNA therapies
Therapeutics based on messenger RNA, or mRNA, can potentially treat a wide range of maladies,…
Browsing: Publications
VASA-seq – high-throughput total RNA sequencing in single cells
Most methods for single-cell transcriptome sequencing amplify the termini of polyadenylated transcripts, capturing only a…
ResPAN – a powerful batch correction model for scRNA-seq data through residual adversarial networks
With the advancement of technology, we can generate and access large-scale, high dimensional and diverse…
Researchers develop online portal to show how biases in RNA sequences affect gene expression
A recent publication from researchers at the University of Kentucky explains the importance of identifying…
Transcriptional recording enables noninvasive measurement of the intestinal tract with potential for biomedical research and future biomedical diagnostic applications
Bacteria within the gut continuously adapt their gene expression to environmental conditions that are associated…
ActiveSVM – single-cell mRNA-seq data analysis with a minimal number of genes
Sequencing costs currently prohibit the application of single-cell mRNA-seq to many biological and clinical analyses.…
scRNA-Seq draws a a roadmap to future personalized medicine for heart defects that develop before birth
A team of investigators from Texas Heart Institute, Texas Children’s Hospital and Baylor College of…
DestVI – identification of continuums of cell types in spatial transcriptomics data
Most spatial transcriptomics technologies are limited by their resolution, with spot sizes larger than that…
TAS-Seq – terminator-assisted solid-phase cDNA amplification and sequencing for scRNA-seq
The novel terminator-assisted solid-phase complementary DNA amplification and sequencing (TAS-Seq) method provides high-precision data on…
Single-cell map of heart failure suggests possible therapeutic targets
Credit : Maria (Masha) Kost-Alimova and Michelle Melanson, Center for the Development of Therapeutics Fibroblasts,…