eTAM-seq – evolved TadA-assisted N6-methyladenosine sequencing
N6-methyladenosine (m6A), the most abundant internal messenger RNA modification in higher eukaryotes, serves myriad roles…
Browsing: Publications
BOSS-RUNS – streamlining dynamic nanopore sequencing
A new method developed by EMBL-EBI researchers helps to streamline nanopore sequencing in real-time Nanopore…
bulkAnalyseR – an accessible, interactive pipeline for analysing and sharing bulk multi-modal sequencing data
Bulk sequencing experiments (single- and multi-omics) are essential for exploring wide-ranging biological questions. To facilitate…
scMDR – learning cell annotation under multiple reference datasets by multisource domain adaptation
Accurate and efficient cell type annotation is essential for single-cell sequence analysis. Currently, cell type…
Benchmarking full-length transcript single cell mRNA sequencing protocols
Single cell mRNA sequencing technologies have transformed our understanding of cellular heterogeneity and identity. For…
ALPS – an automated live imaging and cell picking system for single-cell RNA sequencing
Single-cell whole-transcriptome analysis is the gold standard approach to identifying molecularly defined cell phenotypes. However,…
Diagnostic potential of the amniotic fluid cells transcriptome in deciphering mendelian disease
A clinical research team from the Department of Paediatrics and Adolescent Medicine and the Department…
tRNA-MaP – functional analyses of RNA-related enzymes using a next-generation DNA sequencer
tRNA-MaP can rapidly analyze the specificity of tRNA m1A22 methyltransferase (TrmK) for substrate tRNAs Genetic…
hECA – A human Ensemble Cell Atlas using data collected from scattered public datasets
Imagine a virtual human body, rich in complexity and detail, that enables scientists to simulate…
A spatially resolved atlas of the human lung characterizes a gland-associated immune niche
Single-cell transcriptomics has allowed unprecedented resolution of cell types/states in the human lung, but their…