Single cell RNA-seq of human cornea organoids
Three-dimensional, lab-grown “mini-corneas” resemble the developing human cornea, making them a powerful new tool for…
Browsing: Publications
The effect of background noise and its removal on the analysis of single-cell expression data
In droplet-based single-cell and single-nucleus RNA-seq experiments, not all reads associated with one cell barcode…
Direct RNA sequencing shows that ‘jumping genes’ help plants adapt to extreme temperature and pathogens
A cutting edge technique, called Direct RNA sequencing, shows that ‘jumping genes’ could be the…
RNA-based amplicon sequencing is ineffective in measuring metabolic activity in environmental microbial communities
Characterization of microbial activity is essential to the understanding of the basic biology of…
Establishing quality control metrics for B cell receptor analysis using the next generation sequencing technologies
With the rapid development and adaptation of next-generation sequencing (NGS) technologies, we have the unprecedented…
UC Irvine neuroscientists develop ‘meta-cell’ to move single-cell transcriptomics forward
New process reveals single-cell secrets for novel therapeutic targets University of California, Irvine neuroscientists probing…
Different genes are expressed at different stages during pregnancy
Findings provide a “normal reference”, describing biological changes that occur in the healthy mother’s blood…
ScInfoVAE – interpretable dimensional reduction of single cell transcription data with variational autoencoders and extended mutual information regularization
Single-cell RNA-sequencing (scRNA-seq) data can serve as a good indicator of cell-to-cell heterogeneity and can…
Single-cell RNA sequencing offers novel insights into the evolution of multiple myeloma
Novel observations of earliest precursor stages among notable findings that could help clinicians intervene earlier…
MAS-ISO-seq – high-throughput RNA isoform sequencing using programmed cDNA concatenation
Full-length RNA-sequencing methods using long-read technologies can capture complete transcript isoforms, but their throughput is…