TEQUILA-seq – a versatile and low-cost method for targeted long-read RNA sequencing
Long-read RNA sequencing (RNA-seq) is a powerful technology for transcriptome analysis, but the relatively low…
Browsing: Publications
CellBender – unsupervised removal of systematic background noise from droplet-based single-cell experiments
Droplet-based single-cell assays, including single-cell RNA sequencing (scRNA-seq), single-nucleus RNA sequencing (snRNA-seq) and cellular indexing…
spinDrop – a droplet microfluidic platform to maximise single-cell sequencing information content
Droplet microfluidic methods have massively increased the throughput of single-cell sequencing campaigns. The benefit of…
GRAB-ALL – a high-throughput pipeline for DNA/RNA/small RNA purification from tissue samples for sequencing
High-throughput total nucleic acid (TNA) purification methods based on solid-phase reversible immobilization (SPRI) beads produce…
contrastiveVI – isolating salient variations of interest in single-cell data
Single-cell datasets are routinely collected to investigate changes in cellular state between control cells and…
Dana-Farber AI-model predicts primary source of cancer using gene sequencing data
Researchers at Dana-Farber Cancer Institute have created an AI-based tool that uses tumor gene sequencing…
Nanopore technology achieves breakthrough in protein variant detection
A team of scientists led by the University of Oxford have achieved a significant breakthrough…
Single-cell sequencing reveals the landscape of the human brain metastatic microenvironment
Brain metastases is the most common intracranial tumor and account for approximately 20% of all…
Single-cell RNA sequencing identifies cause of inner-ear bone loss
Researchers from Osaka University show that the possible cause of local bone erosion in cholesteatomas…
The ENCODE4 long-read RNA-seq collection reveals distinct classes of transcript structure diversity
The majority of mammalian genes encode multiple transcript isoforms that result from differential promoter use,…