sNucConv – a bulk RNA-seq deconvolution method trained on single-nucleus RNA-seq data to estimate cell-type composition
Deconvolution algorithms rely on single-cell RNA-sequencing (scRNA-seq) data applied onto bulk RNA-sequencing (bulk RNA-seq) to…
Browsing: Publications
TimeTalk – decipher cell-cell communication from single-cell RNA-seq datasets
Early embryonic development is a dynamic process that relies on proper cell-cell communication to form…
Single-nucleus RNA sequencing identifies neuronal diversity and candidate mediators of circuit assembly
The superior colliculus (SC) is a sensorimotor structure in the midbrain that integrates input from…
Joint-snhmC-seq – simultaneously profile 5hmC and true 5mC in single cells
Oxidative modification of 5-methylcytosine (5mC) by ten-eleven translocation (TET) DNA dioxygenases generates 5-hydroxymethylcytosine (5hmC), the…
SLAM-Drop-seq reveals mRNA kinetic rates throughout the cell cycle
RNA abundance is tightly regulated in eukaryotic cells by modulating the kinetic rates of RNA…
scProjection – projecting RNA measurements onto single cell atlases to extract cell type-specific expression profiles
Multi-modal single cell RNA assays capture RNA content as well as other data modalities, such…
Eye atlas pinpoints where disease-causing genes are expressed, raising hope for inroads against blindness
Glaucoma and macular degeneration cause blindness in millions of people every year. Hundreds of genes…
How flies develop sight – scientists use single-cell sequencing to identify cell types in the visual system
Researchers discover new types of cells in the brain of developing flies thanks to a…
smRandom-seq – droplet-based high-throughput single microbe RNA sequencing
Bacteria colonize almost all parts of the human body and can differ significantly. However, the…
Spatiotemporal RNA sequencing of the mouse brain identifies gene ‘fingerprint’ for brain aging
A study in mice finds that white matter — the tissue that transmits messages around…