Unraveling the complex cellular composition of aldosterone-producing adenomas with single-nucleus RNA sequencing
Researchers from Tokyo Medical and Dental University (TMDU) find that the cells that make up…
Browsing: Publications
Learning and memory problems in down syndrome linked to alterations in genome’s ‘dark matter’
Researchers at the Centre for Genomic Regulation (CRG) reveal that the Snhg11 gene is critical for the…
Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals with TempO-Seq
In the realm of toxicology, assessing the potential genotoxicity of chemicals is crucial for safeguarding…
BOLT-seq – cost and time-efficient construction of a 3′-end mRNA library from unpurified bulk RNA in a single tube
Unraveling the transcriptome—the complete set of RNA molecules in a cell—is pivotal for understanding gene…
RNA-sequencing analysis reveals key genes behind eggplant peel variation
Anthocyanins give fruits and vegetables their red, purple, and blue colors, offering health benefits. Their…
Single-molecule RNA sizing enables quantitative analysis of alternative transcription termination
Transcription, the process of synthesizing RNA from DNA, lies at the heart of molecular biology…
TSS-seq2 – an improved method for the highly specific detection of transcription start sites
Understanding gene transcription—the process by which genetic information encoded in DNA is converted into RNA—is…
rMATS-turbo – an efficient and flexible computational tool for alternative splicing analysis of large-scale RNA-seq data
The process of alternative splicing adds a layer of complexity to the way genetic information…
CANAL – continually adapting pre-trained language model to universal annotation of single-cell RNA-seq data
Annotating cell types within single-cell RNA sequencing (scRNA-seq) datasets has posed a significant challenge, especially…
Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data
In the realm of molecular biology, understanding the intricate processes of RNA synthesis and turnover…