Single cell quantification of microRNA from small numbers of non-invasively sampled primary human cells
Expression levels of microRNAs (miRNAs) in single cells are low and conventional miRNA detection methods…
Browsing: Publications
CloneTracer – clonally resolved single-cell multi-omics
Researchers have developed a new method to distinguish between cancerous and healthy stem cells and…
BEERS2 – RNA-Seq simulation through high fidelity in silico modeling
Simulation of RNA-seq reads is critical in the assessment, comparison, benchmarking, and development of bioinformatics…
Researchers identify unique biomarker patterns identifying severe COVID in children
Using powerful RNA sequencing technology, researchers have identified specific biomarker patterns in the blood that…
HaploCoV – unsupervised classification and rapid detection of novel emerging variants of SARS-CoV-2
Accurate and timely monitoring of the evolution of SARS-CoV-2 is crucial for identifying and tracking…
Read2Tree – inference of phylogenetic trees directly from raw sequencing reads
Current methods for inference of phylogenetic trees require running complex pipelines at substantial computational and…
Gene filtering strategies for machine learning guided biomarker discovery using neonatal sepsis RNA-seq data
Machine learning (ML) algorithms are powerful tools that are increasingly being used for sepsis biomarker…
A systems biology approach uncovers novel disease mechanisms in age-related macular degeneration
Age-related macular degeneration (AMD) is a leading cause of blindness, affecting 200 million people worldwide.…
Researchers combine RNA-Seq datasets and apply Uniform Manifold Approximation and Projection (UMAP) to create new brain atlas
Sometimes, in the quest for new data, scientists forget that existing datasets can be treasure…
An intuitive guide to processing RNA-seq reads
The RNA sequencing technique known as ‘RNA-seq’ captures the expressed genes by sequencing the RNA…