Direct RNA Sequencing and FLAM-seq reveal the site of transcription start often determines the site of transcription end
Each gene in our DNA has a beginning and an end. Defining the gene’s extremities…
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Single-cell transcriptomic analysis uncovers diverse and dynamic senescent cell populations
Senescence is a state of enduring growth arrest triggered by sublethal cell damage. Given that…
Researchers use RATESeq to measure the rate of both transcription and breakdown of RNA molecules in human disease
Every cell in our body is able to turn genes (DNA) on or off, producing…
Researchers identify unique biomarker patterns identifying severe COVID in children
Using powerful RNA sequencing technology, researchers have identified specific biomarker patterns in the blood that…
Study highlights the power of single-nucleus RNA sequencing and spatial transcriptomics to uncover facets of disease biology
Brain metastases in patients with kidney cancer may have immune-suppressive tumor microenvironments Researchers applied single-nucleus…
OHSU researchers assemble most extensive atlas of human gene mutations
With hundreds of tissue donors, it is the most extensive guide ever created; could lead…
TEMPOmap – a method that uncovers subcellular RNA profiles across time and space at the single-cell level
TEMPOmap can follow thousands of newly made RNA molecules within a cell simultaneously, revealing new…
Single-cell RNA sequencing determines the evolutionary age of individual cell types
A research team led by Dr Chaogu ZHENG from the School of Biological Sciences at…
Can single-cell transcriptomics tell us if our brain is capable of repairing itself?
Is our brain able to regenerate? And can we harness this regenerative potential during aging…
ProBac-seq – probe-based bacterial single-cell RNA sequencing
Clonal bacterial populations rely on transcriptional variation across individual cells to produce specialized states that…