A lineage tree-based hidden Markov model quantifies cellular heterogeneity and plasticity
Individual cells can assume a variety of molecular and phenotypic states and recent studies indicate…
Browsing: Publications
New statistical method improves RNA-Seq analyses
A new statistical method provides a more efficient way to uncover biologically meaningful changes in…
RNA sequencing unlocks pattern of gene activity for ADHD
New study uses postmortem brain tissues to understand genomic differences in individuals with attention deficit…
First use of transcriptomics as a blood test to measure RNA levels in patients with long-term Lyme disease
Researchers at the Icahn School of Medicine at Mount Sinai in New York have identified…
RNA sequencing from FFPE tissues for spatial gene expression analysis
Spatial transcriptome analysis of formalin-fixed paraffin-embedded (FFPE) tissues using RNA-sequencing (RNA-seq) provides interactive information on…
New methods maps how breast cancer spreads
New technology can trace which populations of breast cancer cells are responsible for the spread…
rG4-seq 2.0 – enhanced transcriptome-wide RNA G-quadruplex sequencing for low RNA input samples
RNA G-quadruplexes (rG4s) are non-canonical structural motifs that have diverse functional and regulatory roles, for…
Systematic characterization of cancer transcriptome at transcript resolution
Transcribed RNAs undergo various regulation and modification to become functional transcripts. Notably, cancer transcriptome has…
Covid virus alters RNA in infected cells
For the first time, scientists at the Federal University of São Paulo (UNIFESP) in Brazil…
The untapped potential of RNA structures
The human genome has just over 20,000 genes coding for proteins. Yet, it produces at…