Single-nuclei RNA sequencing detects gene splicing defect known as “cryptic exons” in ALS
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are devastating neurodegenerative diseases with mean survival…
Browsing: Publications
New sequencing methods reveal the RNA secrets of extreme microorganisms
Regensburg researchers decode the step-by-step ribosome biosynthesis in archaea. Archaea are microscopic life forms that…
Researchers develop an innovative approach to classify metastases in patients with colorectal cancer from mRNA and miRNA expression profiles
Once cancer spreads to different parts of the body (known as metastasis), it is more…
Single-cell atlas of the human kidney provides new resources to study kidney disease
What causes certain individuals who experience a sudden decline in kidney function to develop kidney…
Otago University-led research delivers more certainty for genetic test diagnoses
Findings from a new international study look set to improve rates of diagnosis for patients…
HuBMAP – what healthy human tissue looks like
Stanford Medicine scientists describe details of the human intestine and placental tissue as part of…
cellCounts – an R function for quantifying 10x Chromium single-cell RNA sequencing data
The 10x Genomics Chromium single-cell RNA sequencing technology is a powerful gene expression profiling platform,…
Unraveling the mystery of semi-extractable RNAs from human cell lines
Researchers characterize semi-extractable RNAs and create the first ever data set that may decode RNA-driven…
Mandalorion – identifying and quantifying isoforms from accurate full-length transcriptome sequencing reads
Researchers from the University of California Santa Cruz have developed and benchmarked Mandalorion v4.1 for…
A novel cell membrane-associated RNA extraction method
Cell membrane-associated RNA (mem-RNA) has been demonstrated to be cell-specific and disease-related and are considered…