Worm Perturb-Seq – massively parallel whole-animal RNAi and RNA-seq
Understanding how genes control biological processes is a fundamental goal of genetics. One powerful way…
Browsing: Publications
RNA sequencing reveals NEAT1 depletion disrupts autophagy in Rett syndrome
Researchers at the Josep Carreras Leukaemia Research Institute revealed a new aspect of Rett Syndrome’s…
RNA sequencing reveals soybean’s genetic defense against nematode pathogens
“Fight-or-flight” is not an option for plants, unfortunately, when it comes to pathogen attacks. Instead,…
MrHAMER2 – high-accuracy long-read RNA sequencing to decode isoform-specific variation in viral transcripts during latency
The ability of HIV to hide in a latent state, lying dormant within host cells,…
Fish environmental RNA sequencing sensitively captures accumulative stress responses through short-term aquarium sampling
Environmental RNA (eRNA) is a technique that allows scientists to track biological responses to environmental…
IBDverse – the largest single-cell RNA sequencing dataset of terminal ileal biopsies
Crohn’s disease (CD) is a long-term condition that causes inflammation in the digestive system, often…
VeloVGI – accurate RNA velocity estimation based on multibatch network reveals complex lineage in batch scRNA-seq data
When scientists want to understand how cells grow, change, and develop, they often turn to…
Combining long- and short-read sequencing in single cells reveals new mRNAs in neurodegenerative diseases
3D rendering of a strand of messenger RNA Scientists at Sanford Burnham Prebys used two…
Single-cell RNA sequencing of chronic idiopathic erythroderma defines disease-specific markers
Chronic idiopathic erythroderma (CIE) is a complex skin disorder characterized by widespread redness and inflammation,…
O-MAPping the cell for a spatial understanding of basic biology
From the Cancer Consortium Shechner lab, Department of Pharmacology, University of Washington Mapping is crucial…