Transfer RNAs (tRNAs) are critical molecules involved in protein synthesis, but they can be tough to analyze. This is mainly because tRNAs are highly modified, making traditional methods like reverse transcription and RNA sequencing (RNAseq) unreliable for accurately quantifying them. However, researchers at Johannes Gutenberg University Mainz have now developed a new approach that …
DORQ-seq – high-throughput quantification of femtomol tRNA pools by combination of cDNA hybridization and deep sequencing
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