Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation
Our ability to feel sensations like touch, pain, and temperature relies on a group of…
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Seq-Scope – repurposing Illumina sequencing flow cells for high-resolution spatial transcriptomics
Spatial transcriptomics (ST) is reshaping how scientists study gene expression in tissues. Traditional methods like…
QUIC-seq – quick ultra-affordable high-throughput convenient RNA sequencing
Understanding how genes function and regulate biological processes requires accurate measurement of transcript levels, which…
PROFIT-seq – real-time and programmable transcriptome sequencing
The eukaryotic transcriptome is incredibly complex, with many types of RNA molecules—including messenger RNAs (mRNAs),…
scCaT – an explainable capsulating architecture for sepsis diagnosis transferring from single-cell RNA sequencing
Sepsis is a serious medical condition that occurs when the body has an extreme response…
scNanoSeq-CUT&Tag – single-cell long-read sequencing method for chromatin modification profiling
A significant aspect of gene regulation is the structure of chromatin, which is a combination…
BACS – absolute quantitative and base-resolution sequencing reveals comprehensive landscape of pseudouridine across the human transcriptome
Pseudouridine (Ψ) is a common modification found in RNA, the molecule that plays a vital…
SPEAC-seq – droplet-based functional CRISPR screening of cell–cell interactions
Cell-to-cell communication is vital for the proper functioning of tissues in our bodies. Every action,…
Use of synthetic circular RNA spike-ins (SynCRS) for normalization of circular RNA sequencing data
High-throughput RNA sequencing has revolutionized how scientists study gene expression, enabling us to measure the…
scRICA-seq – simultaneous profiling of RNA isoforms and chromatin accessibility of single cells
Researchers at Sun Yat-Sen University have made an exciting breakthrough in understanding how neurons develop,…