Single-nucleus total RNA sequencing of formalin-fixed paraffin-embedded samples using snRandom-seq
Formalin-fixed paraffin-embedded (FFPE) tissue samples are a cornerstone of clinical research and pathology. These preserved…
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TRADE – ranscriptome-wide analysis of differential expression
CRISPR technology has made it possible to systematically explore the effects of turning genes on…
Transcriptomic profiling of individual bacteria by MATQ-seq
Understanding how individual bacterial cells behave—even when they’re part of the same population—has always been…
Worm Perturb-Seq – massively parallel whole-animal RNAi and RNA-seq
Understanding how genes control biological processes is a fundamental goal of genetics. One powerful way…
O-MAPping the cell for a spatial understanding of basic biology
From the Cancer Consortium Shechner lab, Department of Pharmacology, University of Washington Mapping is crucial…
HIPSD&R-seq – scalable genomic copy number and transcriptome profiling
Understanding cancer at the cellular level is crucial for developing better treatments and therapies. One…
RiboD-PETRI – an improved bacterial single-cell RNA-seq reveals biofilm heterogeneity
Bacterial cells, unlike mammalian cells, do not have mRNA polyadenylated tails, which presents a challenge…
SoupLadle – label-free single-cell RNA multiplexing leveraging genetic variability
Single-cell RNA sequencing (scRNA-seq) is revolutionizing our understanding of human biology, especially in how cells…
MoPEDE – combining RNA sequencing and brain measurements to advance epilepsy treatment
Researchers from Professor Vijay Tiwari’s research group at the Department of Molecular Medicine, University of…
PhOxi-seq – detecting enzyme-dependent m2G in multiple RNA types
RNA is more than just a messenger carrying genetic instructions—it undergoes complex modifications that can…