SLAM-RT&Tag – spatiotemporal profiling of RNA within nuclear compartments in situ
The nucleus of a cell contains several specialized regions known as nuclear compartments. These compartments…
Browsing: Workflow
Bacteria: recording gene activity more efficiently
Analysing the gene activity of every single bacterial cell in a colony? A new technique…
TIRE-seq simplifies transcriptomics via integrated RNA capture and library preparation
RNA sequencing (RNA-seq) has become a go-to method for exploring how genes are expressed across…
Single-nucleus total RNA sequencing of formalin-fixed paraffin-embedded samples using snRandom-seq
Formalin-fixed paraffin-embedded (FFPE) tissue samples are a cornerstone of clinical research and pathology. These preserved…
TRADE – ranscriptome-wide analysis of differential expression
CRISPR technology has made it possible to systematically explore the effects of turning genes on…
Transcriptomic profiling of individual bacteria by MATQ-seq
Understanding how individual bacterial cells behave—even when they’re part of the same population—has always been…
Worm Perturb-Seq – massively parallel whole-animal RNAi and RNA-seq
Understanding how genes control biological processes is a fundamental goal of genetics. One powerful way…
O-MAPping the cell for a spatial understanding of basic biology
From the Cancer Consortium Shechner lab, Department of Pharmacology, University of Washington Mapping is crucial…
HIPSD&R-seq – scalable genomic copy number and transcriptome profiling
Understanding cancer at the cellular level is crucial for developing better treatments and therapies. One…
RiboD-PETRI – an improved bacterial single-cell RNA-seq reveals biofilm heterogeneity
Bacterial cells, unlike mammalian cells, do not have mRNA polyadenylated tails, which presents a challenge…