FedPyDESeq2 – a federated framework for bulk RNA-seq differential expression analysis

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RNA sequencing (RNA-seq) has opened up new frontiers in understanding gene activity and its role in health and disease. However, when researchers work with sensitive patient data—especially data collected from multiple institutions—sharing and combining information becomes a tricky balancing act. On one hand, pooling data can lead to deeper insights and more robust statistical …

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