From Frontline Genomics by Liam Little
Single-cell RNA sequencing (scRNA-seq) has become the most established and widely used technique within single-cell analysis. Spatial transcriptomics is quickly following in the footsteps of scRNA-seq, with spatially resolved transcriptomics named Method of the Year by Nature in 2020.
Single-cell transcriptomics, or scRNA-seq, is widely used for analysing the transcriptome of single-cell populations. With scRNA-seq, gene expression profiling can explore genotype-phenotype relationships at the fine-grained single-cell level.