Single-nucleus total RNA sequencing of formalin-fixed paraffin-embedded samples using snRandom-seq

Formalin-fixed paraffin-embedded (FFPE) tissue samples are a cornerstone of clinical research and pathology. These preserved samples hold a treasure trove of information, often linked to detailed patient histories, disease progressions, and treatment outcomes. However, unlocking their molecular information, especially at the single-cell or single-nucleus level, has been extremely difficult because the preservation process can …