RNA sequencing unlocks non-destructive selection of high-quality brain organoids for cell replacement therapy

By combining morphological and single-cell level gene expression analyses, a team of researchers led by Professor Jun Takahashi (Department of Clinical Application) has established a new non-destructive system to select high-quality brain organoids as a potential tissue source for cell replacement therapy to treat patients after stroke or traumatic brain injuries. Organoids, or self-organizing miniature organs, …