Single-cell RNA-seq reveals the transcriptional program underlying tumor progression and metastasis in neuroblastoma

Neuroblastoma (NB), the most prevalent extracranial solid tumor in children, poses a significant therapeutic challenge due to its metastasis and high heterogeneity. A recent study at Tianjin Medical University leveraging single-cell RNA sequencing (scRNA-seq) has uncovered vital molecular mechanisms underlying NB’s progression and metastasis, shedding light on potential therapeutic targets. The research analyzed primary …