The New York Genome Center is looking for a highly motivated, independent but team-oriented Associate Scientist I with experience in next-generation sequencing to work in their high throughput production lab. This position reports to the Sequencing Supervisor.
Key Responsibilities
- Carry out procedures associated with DNA & RNA for sequencing platforms, including DNA/RNA sample extraction, quantification & preparation, genotyping, library preparation, and sequencer operation;
- Perform quality control of initial samples and sequencing ready final library samples;
Perform sample nucleic acid extractions; - Track all work and issues in the appropriate databases and Laboratory Information Management Systems (LIMS);
- Become proficient using NYGC’s LIMS tracking system to accurately perform day-to-day tasks.
- Maintain, troubleshoot and perform day-to-day work on the Sequencing equipment (e.g. Illumina NovaSeqs, UG, ONT);
- Analyze current process procedures and provide feedback for their optimization and improvement, documenting processes, proposing method improvements, and troubleshooting assays as needed;
- Author/edit standard operating procedures;
- Conduct other laboratory work, as needed;
Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities, and activities may change.
Requirements & Qualifications
- Bachelors’ degree in Molecular Biology, Biotechnology, Biochemistry or related field, plus laboratory experience in nucleic acid research required;
- 1 year of experience in a molecular biology lab with at least 1+ years of demonstrated experience with next-generation sequencing library prep protocols and sequencing preferred;
- Experience with automated liquid handlers preferred;
- Solid knowledge of molecular biology equipment and related protocols (including RNA and DNA preparation, RNA and DNA quantification, hybridization, PCR, multiplex amplification and bead-based solutions) highly preferred;
- Familiarity with Microsoft Word, Excel, and PowerPoint, preferably with Mac OS;
- Good general laboratory and organizational skills, including the ability to work independently and efficiently are essential;
- Ability to multitask is a must, along with an orientation toward teamwork and cooperation;
- Strong creative thinking and problem-solving skills; and,
- Excellent communication skills required.
