Circular RNA (circRNA) is a unique type of non-coding RNA produced by back splicing of mRNA to form the covalent junction without 3’-5’ polarity and poly(A) tail. CircRNA was first discovered about 30 years ago and was considered a byproduct of abnormal splicing without regulatory function. In 2013, it is the regulatory mechanism of circRNA …
Advances in the molecular diagnostic methods for circular RNA
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